Forthcoming

Culprit Lesion Characteristics and Outcomes of Myocardial Infarction during The Month of Ramadan among Fasting Muslims Population

Authors

  • Mohamed A Khalil Cardiovascular Department, Tanta University, Egypt
  • Mohamed Khalfallah Cardiovascular Department, Tanta University, Egypt
  • Ahmed Metawee Internal Medicine Department, Tanta University, Egypt
  • Mahmoud Elgawesh Internal Medicine Department, Tanta University, Egypt
  • Ayman Elsheikh Cardiovascular Department, Tanta University, Egypt

Abstract

Objectives: This study aims to investigate the characteristics of culprit lesions and outcomes of myocardial infarction (MI) in fasting Muslims during Ramadan, compared to those in non-Ramadan periods.

Methodology: This study included 138 patients diagnosed with myocardial infarction (both ST elevation and non-ST elevation) who were referred for primary percutaneous coronary intervention (PPCI) or an early invasive strategy during Ramadan (Group I: the fasting group). For comparison, 131 patients with myocardial infarction, referred for PPCI or an early invasive strategy in non-Ramadan months, were included in Group II (the non-fasting group). We compared the culprit lesion characteristics and clinical outcomes of MI between these two groups.

Results: The incidence of myocardial infarction was similar during Ramadan and outside of it. However, significant differences were observed in the culprit lesion characteristics and outcomes between the two groups. During Ramadan, culprit lesions exhibited non-atheromatous characteristics with a heavier thrombus burden in Group I. The use of aspiration catheters during PCI was more frequent, and the decision to defer stenting was significantly higher in this group. Favorable metabolic changes, such as lower blood glucose, serum CRP, total cholesterol, and LDL, were noted in the fasting group; however, these changes did not significantly impact the overall clinical outcomes between the groups.

Conclusion: Myocardial infarction during Ramadan is characterized by non-atheromatous coronary lesions and a higher thrombus burden. Despite these differences, the incidence of myocardial infarction and major adverse cardiac events did not significantly differ between Ramadan and other months of the year.

Downloads

Download data is not yet available.

Downloads

Published

2024-10-14

How to Cite

1.
Khalil MA, Khalfallah M, Metawee A, Elgawesh M, Elsheikh A. Culprit Lesion Characteristics and Outcomes of Myocardial Infarction during The Month of Ramadan among Fasting Muslims Population. Pak Heart J [Internet]. 2024Oct.14 [cited 2024Nov.21];. Available from: https://pakheartjournal.com/index.php/pk/article/view/2779

Issue

Ahead of Print

Section

Original Article

License

Copyright (c) 2021 Pakistan Heart Journal

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

When an article is accepted for publication in the print format, the author will be required to transfer exclusive copyright to the PHJ and retain the rights to use and share their published article with others. However, re-submission of the full article or any part for publication by a third party would require prior permission of the PHJ.

Online publication will allow the author to retain the copyright and share the article under the agreement described in the licensing rights with creative commons, with appropriate attribution to PHJ. Creative Commons attribution license CC BY 4.0 is applied to articles published in PHJ https://creativecommons.org/licenses/by/4.0/