IMMEDIATE OUTCOMES OF PERCUTANEOUS TRANSVENOUS MITRAL COMMISSUROTOMY OF PATIENTS WITHSEVERE MITRAL STENOSIS IN DIFFERENT AGE GROUPS

Abstract

Objectives: To evaluate the immediate outcomes of PTMC for severe mitral valvestenosis.

Methodology: This cross sectional study was conducted from January 2015 toDecember 2015 at Cardiology Department Jinnah hospital Lahore. Patients withsevere mitral valve stenosis having Mitral valve area (MVA) 1.0 cm whounderwent PTMC with suitable valve morphology. All patients underwent PTMCusing the transseptal antegrade technique, after informed consent was obtained.Echocardiography was performed in all patients before and after PTMC to assessthe severity of mitral regurgitation. Patients were divided in two groups based onyounger < 35 years and older age (36 - 60 y) and comparison was made toassess difference before and after intervention. Independent t-test and Chisquaretest was used to assess difference in severity of Mitral stenosis before andafter PTMC in different age groups with p<0.05 as statistical significant.

Results: A total of 60 subjects with severe mitral stenosis underwent PTMC.Mean age was 29.98 ± 10.824 years.The younger group <35 years were 68.3% and 31.7% were older between 36-60 years. There were 88.3% female. Meanpre and post PTMC MVA was 0.83±0.133 and 1.53±0.383 cm (t=2.172 p< .034) respectively. Similarly mean pre and post PTMC MVPG was 27.20 ±6.802 and 12.88±6.3813 (t=4.591 p<.000). The success rate of the PTMCwas significantly higher among 10-35 years 87.8% than 36-60 years 52.7 % (X=8.979 p =.003).

Conclusion: PTMC is a safe and effective treatment for patients with severe MSwho have suitable valve morphology especially in younger age.

Key Words: Mitral Stenosis, PTMC, Mitral Valve Area, Mitral Regurgitation