COMPARISON OF SERUM LIPIDS, LIPOPROTEINS AND APOLIPOPROTEINS IN PATIENTS UNDERGOING CABG WITH HEALTHY ADULTS

Authors

  • ASAL KHAN TAREEN
  • ABDUL SAMAD ACHAKZAI
  • LIAQUAT CHEEMA
  • ANWAR ALI
  • MUHAMMAD REHMAN

DOI:

https://doi.org/10.47144/phj.v40i3-4.46

Keywords:

Lipoprotein (Lp.), Apolipoprotein (Apo), Triacylglycerols (TAG), Coronary Artery Bypass Graft (CABG), Coronary Artery Disease (CAD)

Abstract

OBJECTIVE:
To assess the pattern of plasma lipoproteins in CAD patients including comparison between diabetic and
non-diabetic subgroups.
METHODS:
This case control study was conducted at National Institute of Cardiovascular Diseases (NICVD) Karachi on
patients admitted for CABG from June, 2000 to June, 2001. A total of 100 patients and 100 healthy subjects
were enrolled during the study. 38 patients (38%) were diabetic with mean age of 46.16 years and 62 patients
(62%) were non-diabetic with mean age of 45.26 years. Serum lipids, apolipoproteins A, apolipoproteins B
and Lp(a) of each subject were analysed. One way ANOVA and 95% confidence interval for mean were
applied to find the association of CAD with age, BMI, glucose, cholesterol, triacylglycerols, HDL-c, LDL-c,
and Lp(a).
RESULT:
CABG patients had significantly higher blood TAG levels than controls. Similar results were observed for
HDL-c, which was significantly lower when compared with control subjects. Apo-B and Lp(a) in controls
were significantly lower than both diabetic and non-diabetic CAD patients. The level of Apo-B in diabetic
CAD was significantly higher when compared with control subjects.

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How to Cite

1.
TAREEN AK, ACHAKZAI AS, CHEEMA L, ALI A, REHMAN M. COMPARISON OF SERUM LIPIDS, LIPOPROTEINS AND APOLIPOPROTEINS IN PATIENTS UNDERGOING CABG WITH HEALTHY ADULTS. Pak Heart J [Internet]. 2012May8 [cited 2024Nov.23];40(3-4). Available from: https://pakheartjournal.com/index.php/pk/article/view/46

Issue

Vol. 40 No. 3-4 (2007): Pakistan Heart Journal

Section

Original Article

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