Association of Vasoactive-Inotropic Score with Postoperative Outcomes in Children with Congenital Heart Diseases Undergoing Cardiac Surgery

Authors

  • Rajab Ali Khokhar National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Zubair Ahmed National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Mujeeb Ur Rehman National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Saad Bader Zakai National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Ammad Hussain National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Mahwish Mahboob Bhutta National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Abdul Sattar Shaikh National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Sohail Khan Bangash National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan

DOI:

https://doi.org/10.47144/phj.v57i1.2533

Abstract

Objectives: This cross-sectional study aimed to evaluate the association between the vasoactive-inotropic score (VIS) and post-operative morbidity and mortality in pediatric patients undergoing cardiac surgery for congenital heart diseases (CHDs).

Methodology: A cross-sectional study was conducted at the Pediatric Cardiac Intensive Care Unit (PCICU) of the National Institute of Cardiovascular Diseases, Karachi, Pakistan, between October 2021 and March 2022. A total of 101 children up to 18 years of age admitted to the PCICU were included in the analysis. Demographic characteristics and peri-operative variables were recorded, and VIS scores were collected to assess their association with post-surgery outcomes. A score of ≥15 was considered high, while a score <15 was considered low.

Results: Among the 101 children included in the study, 49 (48.5%) were male and 52 (51.5%) were female, with a mean age of 7.45±2.81 years. Fifteen (14.9%) patients had a high VIS score during their ICU stay, while 86 patients had a low VIS score. Low cardiac output was the most common post-operative morbidity observed in 9 (8.9%) children, followed by hepatic dysfunction and acute kidney injury, each reported in 8 (7.9%) children. Significant associations were found between high VIS and hepatic dysfunction (p<0.001), acute kidney injury (p<0.001), low cardiac output (p<0.001), neurological dysfunction (p=0.016), and mortality (p<0.001).

Conclusion: High VIS scores were significantly associated with poor short-term morbidity and mortality in children undergoing corrective surgery for CHDs. The VIS system can aid in predicting disease progression, severity, and outcomes in pediatric cardiac surgical patients.

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Published

2024-03-30

How to Cite

1.
Khokhar RA, Ahmed Z, Rehman MU, Zakai SB, Hussain A, Bhutta MM, Shaikh AS, Bangash SK. Association of Vasoactive-Inotropic Score with Postoperative Outcomes in Children with Congenital Heart Diseases Undergoing Cardiac Surgery. Pak Heart J [Internet]. 2024Mar.30 [cited 2024Jun.16];57(1):38-41. Available from: https://pakheartjournal.com/index.php/pk/article/view/2533

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Original Article