Reaven’s Quartet (Metabolic Syndrome X): A Potent Predictor Of Coronary Events

Abstract

INTRODUCTION:
That Diabetes Mellitus is an independent and major risk factor for coronary events is well known’2’4. The risk for cardiovascular abnormalit Ies is approximately three times higher in diabetic patients5. Acute myo cardi al in farcti on represents the most common manifestation of IHD in adult diabetics. Angina, asymptomatic IHD, and congest ive cardiac failure account for the remainder. Other manifestations of accelerated athero scieros is like strokes6 and peripheral vascular disease also have an increased incidence7.

MATERIAL AND METHODS:
400 patients with ischemic heart disease adm itted to medical units of Holy Family Hospital between 1989 & 1992 were included in the study. The criteria for selection was patients with angina, clear evidence of acute myocardial infarction at least three months prior to their entry in to the study, and other evidence of ischemic heart dise ase, congestive cardiac failure or asymptomatic ischemia. All patients had a detailed history, a detailed physical examination and were screened for diabetes according to current WHO recommend ations. Lipid estimations were done after an over night fast.

RESULTS:
A total of 400 patients with ischemic heart disease were included in the first part of the study. The frequency of type of ischemic heart disease was infarctions 36%, angina 9%, chronic coronary artery discase 36% jFig 1.36.

CONCLUSION:

This study emphasizes the importance of identifying the clustcring of risk factors in the diabetics with coronary artery disease and confirms the presence of Reaven’s Syndrome’s Quartet.