FREQUENCY OF CONTRAST INDUCED NEPHROPATHY IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION

Abstract

Objectives: To determine the frequency of contrast induced nephropathy (CIN) in
patients undergoing percutaneous coronary intervention (PCI)

Methodology: This was descriptive cross sectional study performed at
Cardiology Department Hayatabad Medical Complex Peshawar from 1 July
2014 to 31 Dcember 2014. Patients who were admitted for PCI, were included in
the study. Sampling techniques was non probability consecutive. Contrast
induced nephropathy was defined as increase in serum creatinin of 25% or more
from the baseline value and/or an absolute increase of 0.5 mg/dl or more in
serum creatinin from baseline value. Data was analyzed using SPSS version-15.
All results were presented in the formof tables and graphs.

Results: A total of 177 patients, who were admitted in Cardiology Department
Hayatabad Medical Complex Peshawar for PCI were included in the study. Mean
Age of the study population was 60±5.71 years. Frequency of contrast induced
nephropathy among 177 patients was analyzed and it was found that 18(10%)
patients developed contrast induced nephropathy during hospital stay. There was
no gender difference in the frequency of CIN but it was found that CIN was more
common in advanced age group. Regarding patients clinical presentation it was
found that CIN was more common in patients who presented with ACS than in
patients with stable angina.

Conclusion: Contrast induced nephropathy is a common finding following PCI
which is more common in patients with advance age and presenting with acute
coronary syndrome.

Key Words: Percutaneous Coronary Intervention, Contrast Induced
Nephropathy, Diabetes Mellitus