THREE MONTHS CLINICAL OUTCOMES OF DRUG ELUTING STENTS IN PATIENTS WITH STABLE ANGINA PECTORIS

Abstract

Objective: The objective of this study was to determine the frequency of three
months clinical outcomes of Drug Eluting Stents in patients with stable angina
pectoris.

Methodology: This was a cross sectional descriptive study. Patients who were
admitted to Cardiology unit Lady Reading Hospital through OPD or casualty
department were included in the study. Our study included all the patients with
stable coronary artery disease who had received Drug eluting stents from April
01 2011 to July 31 2012. The total study duration was 15 months. The primary
end points were, rate of Myocardial infarction (MI), unstable angina(UA) and
positive ETT at three months. All patients who underwent Percutaneous coronary
intervention with Drug eluting stent for stable angina pectoris were followed and
reassessed after 3 months from the index procedure. Exercise Tolerance Test
(ETT) was performed on every patient and recorded on proforma. Data analysis
was done using SPSS version 16.

Results: A total of 376 patients were included in this study. The mean age was
57±9.313 years. Males were 271(72.1%). Majority of the patients got stented to
Left anterior descending and left circumflex arteries. Mean length of drug eluting
stent was 27.313±7.235 mm while mean diameter of stent was 2.90±0.2483
mm. About 11 (2.9%) patients suffered from MI. About 26 (6.9%) patients had
unstable angina and 37 (9.8%) patients had positive ETT at three months
followup post PCI.

Conclusion: Short-term results from this study suggest that real-world
outcomes among 376 patients are comparable to those reported across other
registries and trials, and safety outcomes as measured by rates of MI, UA and
positive ETT were low. The long-term safety of drug-eluting stents needs to be
ascertained in larger randomized trials.

Key Words: Coronary Artery Disease, Drug Eluting Stents, Stable Angina,
Percutaneous Coronary Intervention